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上腸間膜静脈血栓症にヘパリン起因性血小板減少症を併発した1例
http://hdl.handle.net/10232/00030861
http://hdl.handle.net/10232/0003086165ed6094-a00e-4c33-bdef-b0ad94d18a5e
名前 / ファイル | ライセンス | アクション |
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AN00040104_71_p6-13 (991.3 kB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2020-02-04 | |||||
タイトル | ||||||
タイトル | 上腸間膜静脈血栓症にヘパリン起因性血小板減少症を併発した1例 | |||||
言語 | ja | |||||
タイトル | ||||||
タイトル | Superior Mesenteric Venous Thrombosis Complicated by Heparin-induced Thrombocytopenia : A Case Report | |||||
言語 | en | |||||
著者 |
保坂, 優斗
× 保坂, 優斗× 石神, 純也× 恵, 浩一× 瀬戸山, 徹郎× 夏越, 祥次 |
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言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Superior mesenteric venous thrombosis (SMVT) | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Heparin-induced thrombocytopenia (HIT) | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Pulmonary thromboembolism (PE) | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
要約(Abstract) | ||||||
内容記述タイプ | Other | |||||
内容記述 | A 47-year-old man was referred to our hospital with the chief complaint of abdominal pain. Contrast-enhanced Computed Tomography (CT) revealed thrombus in the superior mesenteric vein. Based on a diagnosis of superior mesenteric venous thrombosis (SMVT), conservative treatment was started with heparin and urokinase. However, CT performed on the following day revealed an area with poor blood flow in the small intestine; therefore, emergency surgery was performed. After resection of approximately 3 m of necrotized small intestine, anastomosis was performed. Immediately after surgery, nafamostat was administered. From postoperative day 3, heparin was continuously administered. On postoperative day 5, pulmonary thrombosis appeared on CT findings; therefore, the heparin dose was increased. Nevertheless, on postoperative day 7, the patient’s platelet count decreased to 54,000 /μl. Therefore, heparin-induced thrombocytopenia (HIT) was suspected, and heparin administration was discontinued, while continuous administration of argatroban was started. Discontinuation of heparin resulted in normalization of platelet count; contrast-enhanced CT indicated that the size of pulmonary thrombosis had decreased. The patient subsequently progressed well and was discharged to his home on postoperative day 28. In SMVT, the formation of a thrombus in the superior mesenteric vein causes impaired blood flow in the intestinal tract, due to congestion. Heparin is primarily used for conservative treatment in the acute phase. HIT is an adverse effect of heparin administration that can sometimes cause severe thromboembolism. Here, we describe a rare case of HIT that occurred during pulmonary thromboembolism treatment following surgery for SMVT. | |||||
言語 | en | |||||
収録雑誌名 |
ja : 鹿児島大学医学雑誌 en : Medical journal of Kagoshima University 巻 71, 号 1-3, p. 6-13, 発行日 2019 |
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作成日 | ||||||
日付 | 2019-06 | |||||
日付タイプ | Issued | |||||
ISSN | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 03685063 | |||||
NII書誌ID(雑誌) | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00040104 | |||||
出版タイプ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
NDC | ||||||
主題Scheme | NDC | |||||
主題 | 490 | |||||
公開者・出版者 | ||||||
出版者 | 鹿児島大学 | |||||
言語 | ja | |||||
公開者・出版者 | ||||||
出版者 | Kagoshima University | |||||
言語 | en |