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The identification of the primary site of OSA is essential to determine treatment strategy. This study aimed to establish computational fluid dynamics (CFD) analysis for determining the clinical severity of OSA and the primary site of OSA.\nMethods: Twenty children (mean age, 6 years) were divided into OSA and control groups according to their apnea hypopnea index. Three-dimensional airways were constructed from computed tomography data. The pharyngeal airway morphology and the pressure and velocity of the upper airway were evaluated using CFD analysis.\nResults: The maximum velocity and pressure of the upper airway in the OSA group were significantly correlated with the severity of OSA (rs = 0.741, P \u003c 0.001; rs = 0.653, P = 0.002). A velocity higher than 12 m/s indicated the primary site of OSA. In addition, we found that the primary site of OSA is not necessarily the same as the collapsible conduit site.\nConclusions: CFD analysis allows both the evaluation of the disease severity of OSA and the identification of the primary site of OSA in children. 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Primary site identification in children with obstructive sleep apnea by computational fluid dynamics analysis of the upper airway
http://hdl.handle.net/10232/00031069
http://hdl.handle.net/10232/00031069d7fc1302-77f0-4b6b-a31f-d1a5b438d230
名前 / ファイル | ライセンス | アクション |
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Item type | 学位論文 / Thesis or Dissertation(1) | |||||
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公開日 | 2020-05-21 | |||||
タイトル | ||||||
タイトル | Primary site identification in children with obstructive sleep apnea by computational fluid dynamics analysis of the upper airway | |||||
別言語のタイトル | ||||||
その他のタイトル | 上気道流体シミュレーションを用いた小児閉塞性睡眠時無呼吸症の原因部位特定方法の確立 | |||||
著者 |
柳澤, 彩佳
× 柳澤, 彩佳 |
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著者よみ | ||||||
姓名 | ヤナギサワ, アヤカ | |||||
別言語の著者 | ||||||
姓名 | YANAGISAWA, Ayaka | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題言語 | en | |||||
主題Scheme | Other | |||||
主題 | computed fluid dynamics | |||||
キーワード | ||||||
主題言語 | en | |||||
主題Scheme | Other | |||||
主題 | children | |||||
キーワード | ||||||
主題言語 | en | |||||
主題Scheme | Other | |||||
主題 | obstruction site | |||||
キーワード | ||||||
主題言語 | en | |||||
主題Scheme | Other | |||||
主題 | primary site | |||||
キーワード | ||||||
主題言語 | en | |||||
主題Scheme | Other | |||||
主題 | obstructive sleep apnea | |||||
キーワード | ||||||
主題言語 | en | |||||
主題Scheme | Other | |||||
主題 | airway velocity | |||||
キーワード | ||||||
主題言語 | en | |||||
主題Scheme | Other | |||||
主題 | airway pressure | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_db06 | |||||
資源タイプ | doctoral thesis | |||||
アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
要約(Abstract) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Study Objectives: Obstructive sleep apnea (OSA) is a respiratory disorder caused by the obstruction of the upper airway during sleep. The identification of the primary site of OSA is essential to determine treatment strategy. This study aimed to establish computational fluid dynamics (CFD) analysis for determining the clinical severity of OSA and the primary site of OSA. Methods: Twenty children (mean age, 6 years) were divided into OSA and control groups according to their apnea hypopnea index. Three-dimensional airways were constructed from computed tomography data. The pharyngeal airway morphology and the pressure and velocity of the upper airway were evaluated using CFD analysis. Results: The maximum velocity and pressure of the upper airway in the OSA group were significantly correlated with the severity of OSA (rs = 0.741, P < 0.001; rs = 0.653, P = 0.002). A velocity higher than 12 m/s indicated the primary site of OSA. In addition, we found that the primary site of OSA is not necessarily the same as the collapsible conduit site. Conclusions: CFD analysis allows both the evaluation of the disease severity of OSA and the identification of the primary site of OSA in children. The primary site of OSA is not necessarily the same as the collapsible conduit site; therefore, CFD analysis can be used to identify the appropriate intervention for treating OSA. |
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要約(Abstract) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Ayaka Yanagisawa-Minami, Takeshi Sugiyama, Tomonori Iwasaki, Youichi Yamasaki Primary site identification in children with obstructive sleep apnea by computational fluid dynamics analysis of the upper airway Journal of Clinical Sleep Medicine 16(3) 2020 https://doi.org/10.5664/jcsm.8224 This article has been accepted for publication in the Journal of Clinical Sleep Medicine published by the American Academy of Sleep Medicine |
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作成日 | ||||||
日付 | 2020-03-06 | |||||
出版タイプ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
NDC | ||||||
主題Scheme | NDC | |||||
主題 | 490 | |||||
ファイル(説明) | ||||||
内容記述タイプ | Other | |||||
内容記述 | 博士論文全文 | |||||
ファイル(説明) | ||||||
内容記述タイプ | Other | |||||
内容記述 | 博士論文要旨 | |||||
ファイル(説明) | ||||||
内容記述タイプ | Other | |||||
内容記述 | 最終試験結果の要旨 | |||||
ファイル(説明) | ||||||
内容記述タイプ | Other | |||||
内容記述 | 論文審査の要旨 | |||||
公開者・出版者 | ||||||
出版者 | American Academy of Sleep Medicine | |||||
公開者・出版者 | ||||||
出版者 | 鹿児島大学 | |||||
公開者よみ | ||||||
公開者よみ | カゴシマ ダイガク | |||||
公開者別名 | ||||||
公開者別名 | Kagoshima University | |||||
備考 | ||||||
備考 | 【指導教員:岩崎智憲】 | |||||
date.appl | ||||||
【学位申請日】2019-12-04 | ||||||
学位名 | ||||||
学位名 | 博士(歯学)Doctor of Philosophy in Dental Science | |||||
学位授与機関 | ||||||
学位授与機関識別子Scheme | kakenhi | |||||
学位授与機関識別子 | 17701 | |||||
学位授与機関名 | 鹿児島大学 | |||||
学位授与年月日 | ||||||
学位授与年月日 | 2020-03-25 | |||||
学位授与番号 | ||||||
学位授与番号 | 甲総研第545号 |