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  1. 医歯学総合研究科
  2. 医歯学総合研究科・博士論文

A new pre-test probability score for diagnosis of deep vein thrombosis in patients before surgery

http://hdl.handle.net/10232/00031991
http://hdl.handle.net/10232/00031991
336a6384-973c-41e5-9ea0-deea36b2bd9a
名前 / ファイル ライセンス アクション
Diss_濱元_裕喜_ISK652_2021.pdf Diss_濱元_裕喜_ISK652_2021 (712.1 kB)
license.icon
Abstract_濱元_裕喜_4518810324_2021.pdf Abstract_濱元_裕喜_4518810324_2021 (79.3 kB)
Result_Hamamoto_Yuki_isk_652.pdf Result_Hamamoto_Yuki_isk_652 (4.4 MB)
Comments_Hamamoto_Yuki_isk_652.pdf Comments_Hamamoto_Yuki_isk_652 (2.0 MB)
Item type 学位論文 / Thesis or Dissertation(1)
公開日 2022-05-27
タイトル
タイトル A new pre-test probability score for diagnosis of deep vein thrombosis in patients before surgery
別言語のタイトル
その他のタイトル 手術前の患者における深部静脈血栓症の診断のための新しい検査前確率スコア
著者 濱元, 裕喜

× 濱元, 裕喜

WEKO 140680

濱元, 裕喜

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著者よみ
姓名 ハマモト, ユウキ
別言語の著者
姓名 HAMAMOTO, Yuki
言語
言語 eng
キーワード
主題言語 en
主題Scheme Other
主題 Before surgery
キーワード
主題言語 en
主題Scheme Other
主題 D-dimer
キーワード
主題言語 en
主題Scheme Other
主題 Deep vein thrombosis
キーワード
主題言語 en
主題Scheme Other
主題 Kagoshima-DVT score
キーワード
主題言語 en
主題Scheme Other
主題 Pre-test probability score
キーワード
主題言語 en
主題Scheme Other
主題 Whole leg ultrasonography
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_db06
資源タイプ doctoral thesis
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
要約(Abstract)
内容記述タイプ Other
内容記述 Background: Venous thromboembolism is a serious perioperative complication. We developed a new pre-test probability score for predicting deep vein thrombosis (DVT) before surgery.
Methods: Whole leg ultrasonography was performed on 973 inpatients and outpatients with suspected DVT based on a preoperative D-dimer cut-off value of ≥ 1 μg/ml. We allocated two-thirds (n = 651) of the study participants to a derivation cohort and one-third (n = 322) to a validation cohort. The pre-test probability model was developed from the derivation cohort data.
Results: The pre-test probability model for DVT assigned 2 points to D-dimer ≥ 1.5 μg/mL and 1 point each to age ≥ 60 years, female sex, ongoing glucocorticoid therapy, prolonged immobility, and cancer with high risk of DVT. The area under the curve of the pre-test probability score was 0.72 and 0.70 in the derivation and validation cohorts, respectively. The rates of DVT according to pre-test probability scores in the derivation and validation cohorts were 7% and 6% in the low (score = 0-2), 23% and 22% in the intermediate (score = 3-4), and 47% and 50% in the high probability group (score ≥ 5), respectively (p < 0.0001).
Conclusions: The pre-test probability score (Kagoshima-DVT score) was helpful in detecting preoperative DVT in both inpatients and outpatients. We identified low probability group to reduce whole-leg ultrasonography and high probability group to detect more DVT before surgery.

Yuki Hamamoto, Akihiro Tokushige, Yuasa Toshinori, Yoshiyuki Ikeda, Yoshihisa Horizoe, Hisayo Yasuda, Takuro Kubozono, Mitsuru Ohishi
A new pre-test probability score for diagnosis of deep vein thrombosis in patients before surgery
Journal of Cardiology 79 (2022) 664–670
作成日
日付 2022-03-04
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
NDC
主題Scheme NDC
主題 490
ファイル(説明)
内容記述タイプ Other
内容記述 博士論文全文
ファイル(説明)
内容記述タイプ Other
内容記述 博士論文要旨
ファイル(説明)
内容記述タイプ Other
内容記述 最終試験結果の要旨
ファイル(説明)
内容記述タイプ Other
内容記述 論文審査の要旨
公開者・出版者
出版者 Elsevier
公開者・出版者
出版者 鹿児島大学
公開者よみ
公開者よみ カゴシマ ダイガク
公開者別名
公開者別名 Kagoshima University
備考
備考 【指導教員:大石充】
date.appl
【学位申請日】2022-01-05
学位名
学位名 博士(医学)Doctor of Philosophy in Medical Science
学位授与機関
学位授与機関識別子Scheme kakenhi
学位授与機関識別子 17701
学位授与機関名 鹿児島大学
学位授与年月日
学位授与年月日 2022-03-11
学位授与番号
学位授与番号 甲総研第652号
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