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  1. 医歯学総合研究科
  2. 医歯学総合研究科・学術誌論文

Sexual excitation induces courtship ultrasonic vocalizations and cataplexy-like behavior in orexin neuron-ablated male mice

http://hdl.handle.net/10232/00032170
http://hdl.handle.net/10232/00032170
ecc127d1-017a-4532-9f37-c2be3a56c572
名前 / ファイル ライセンス アクション
23993642_4_165.pdf 23993642_4_165 (945.3 kB)
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Item type 学術雑誌論文 / Journal Article(1)
公開日 2023-01-12
タイトル
タイトル Sexual excitation induces courtship ultrasonic vocalizations and cataplexy-like behavior in orexin neuron-ablated male mice
タイトル言語 en
著者 Kuwaki, Tomoyuki

× Kuwaki, Tomoyuki

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en Kuwaki, Tomoyuki

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Kanno, Kouta

× Kanno, Kouta

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en Kanno, Kouta

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言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
要約
内容記述タイプ Other
内容記述 Cataplexy is triggered by laughter in humans and palatable food in mice. To further evaluate mice’s cataplexy, we examined courtship behavior in orexin neuron-ablated mice (ORX-AB), one of the animal models of narcolepsy/cataplexy. Wild-type female mice were placed into the home cage of male ORX-AB and cataplexy-like behavior was observed along with ultrasonic vocalizations (USVs), also known as the “love song”. ORX-AB with a female encounter showed cataplexy-like behavior both during the dark and light periods, whereas ORX-AB with chocolate predominantly showed it during the dark period. During the light period observation, more than 85% of cataplexy-like bouts were preceded by USVs. A strong positive correlation was observed between the number of USVs and cataplexy-like bouts. Cataplexy-like behavior in narcoleptic mice is a good behavioral measure to study the brain mechanisms behind positive emotion because they can be induced by different kinds of positive stimuli, including chocolate and female courtship.

Tomoyuki Kuwaki & Kouta Kanno
Sexual excitation induces courtship ultrasonic vocalizations and cataplexy-like behavior in orexin neuron-ablated male mice
Communications Biology 4, 165 (2021)
https://doi.org/10.1038/s42003-021-01696-z
内容記述言語 en
収録雑誌名 en : Communications Biology

巻 4, p. 165, 発行日 2021-02-05
作成日
日付 2021-02-05
日付タイプ Issued
ISSN
収録物識別子タイプ EISSN
ISSN 23993642
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
NDC
主題Scheme NDC
主題 490
公開者・出版者
出版者 Springer Nature
出版者言語 en
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