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日本人一般集団における動脈硬化リスクに対する上腕-足首脈波伝播速度の年齢・性別毎のカットオフ値
http://hdl.handle.net/10232/00032541
http://hdl.handle.net/10232/0003254137a6defa-3157-4878-871e-3abbd3116e2a
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Diss_森_隆子_ISK46_2023 (956.9 kB)
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Abstract_森_隆子_TO_2023 (154.6 kB)
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Result_MORI_Ryuko_isk_46 (127.8 kB)
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Comments_MORI_Ryuko_isk_46 (56.6 kB)
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| Item type | 学位論文 / Thesis or Dissertation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2023-04-28 | |||||
| タイトル | ||||||
| タイトル | Cutoff values of brachial-ankle pulse wave velocity for atherosclerotic risks by age and sex in the Japanese general population | |||||
| タイトル言語 | en | |||||
| タイトル | ||||||
| タイトル | 日本人一般集団における動脈硬化リスクに対する上腕-足首脈波伝播速度の年齢・性別毎のカットオフ値 | |||||
| タイトル言語 | ja | |||||
| 著者 |
森, 隆子
× 森, 隆子 |
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| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Brachial-ankle pulse wave velocity | |||||
| キーワード | ||||||
| 主題言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Suita score | |||||
| キーワード | ||||||
| 主題言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Framingham risk score | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_db06 | |||||
| 資源タイプ | doctoral thesis | |||||
| アクセス権 | ||||||
| アクセス権 | open access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
| 要約 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Aim: In this study, we aim to analyze the correlation between brachial-ankle pulse wave velocity (baPWV) and Suita score or Framingham risk score and obtain the cutoff value of baPWV by sex and age for cardiovascular risk, as assessed by these scores in the large Japanese annual health checkup data. Methods: In total, 25,602 participants (14,539 men and 11,063 women), who had their annual health checkups, were included in this study. Cutoff values of baPWV for the moderate- and high-risk groups stratified by sex and age were obtained using a receiver operating characteristic (ROC) curve analysis. Results: As per our findings, the Suita score demonstrated better correlations with baPWV than the Framingham risk score in both sexes (men, Suita score R2=0.41 and Framingham risk score R2=0.37; women, Suita score R2=0.54 and Framingham risk score R2=0.33). The ROC curve analysis demonstrated the cutoff values of baPWV for moderate- and high-risk groups estimated using the Suita score, and they are as follows: in men, the baPWV cutoff values were 1,350 cm/s in the 40s, 1,430 cm/s in the 50s, 1,520 cm/s in the 60s, and 1,880 cm/s in the 70s. In women, the baPWV cutoff values were 1,350 cm/s in the 40s, 1,430 cm/s in the 50s, 1,570 cm/s in the 60s, and 1,800 cm/s in the 70s. Conclusions: We demonstrated that baPWV significantly correlated with the Suita score or Framingham risk score in both men and women, with the former presenting a stronger correlation than the latter. We propose the cutoff values of baPWV for moderate- and high-risk groups estimated using the Suita score. Ryuko Mori, Masaaki Miyata, Takuro Kubozono, Naoko Inadome, Shin Kawasoe, Satoko Ojima, Takeko Kawabata, Anwar Ahmed Salim, Hironori Miyahara, Kouichi Tokushige, Mitsuru Ohishi Cutoff Values of Brachial-Ankle Pulse Wave Velocity for Atherosclerotic Risks by Age and Sex in the Japanese General Population Journal of Atherosclerosis and Thrombosis 2023; 30: 481-490. https://doi.org/10.5551/jat.63557 |
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| 内容記述言語 | en | |||||
| 作成日 | ||||||
| 日付 | 2023-04-10 | |||||
| 日付タイプ | Collected | |||||
| 出版タイプ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| NDC | ||||||
| 主題Scheme | NDC | |||||
| 主題 | 490 | |||||
| ファイル（説明） | ||||||
| 内容記述 | 博士論文全文, 博士論文要旨, 最終試験結果の要旨, 論文審査の要旨 | |||||
| 公開者・出版者 | ||||||
| 出版者 | Japan Atherosclerosis Society | |||||
| 出版者言語 | en | |||||
| 公開者・出版者 | ||||||
| 出版者 | 鹿児島大学 | |||||
| 出版者言語 | ja | |||||
| 公開者・出版者 | ||||||
| 出版者 | カゴシマ ダイガク | |||||
| 出版者言語 | ja-Kana | |||||
| 備考 | ||||||
| 備考 | 【指導教員:大石充】 | |||||
| date.appl | ||||||
| appl | 【学位申請日】2023-01-04 | |||||
| 学位名 | ||||||
| 学位名の言語 | ja | |||||
| 学位名 | 博士(医学) | |||||
| 学位名 | ||||||
| 学位名の言語 | en | |||||
| 学位名 | Doctor of Philosophy in Medical Science | |||||
| 学位授与機関名 | ||||||
| 学位授与機関識別子Scheme | kakenhi | |||||
| 学位授与機関識別子 | 17701 | |||||
| 学位授与機関名の言語 | ja | |||||
| 学位授与機関名 | 鹿児島大学 | |||||
| 学位授与年月日 | ||||||
| 学位授与年月日 | 2023-04-18 | |||||
| 学位授与番号 | ||||||
| 学位授与番号 | 乙総論第46号 | |||||
