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直腸癌患者における筋膜に沿った発生学を考慮した経肛門的直腸間膜全切除術
http://hdl.handle.net/10232/0002000323
http://hdl.handle.net/10232/00020003239e292bfd-351a-42e0-91cd-bd41b0ae13ed
| Item type | 学位論文 / Thesis or Dissertation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2024-05-17 | |||||
| タイトル | ||||||
| タイトル | Transanal Total Mesorectal Excision Considering the Embryology Along the Fascia in Rectal Cancer Patients | |||||
| タイトル言語 | en | |||||
| タイトル | ||||||
| タイトル | 直腸癌患者における筋膜に沿った発生学を考慮した経肛門的直腸間膜全切除術 | |||||
| タイトル言語 | ja | |||||
| 著者 |
吉満, 工平
× 吉満, 工平 |
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| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | TaTME | |||||
| キーワード | ||||||
| 主題言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | rectal cancer | |||||
| キーワード | ||||||
| 主題言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | PSM | |||||
| キーワード | ||||||
| 主題言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | embryology | |||||
| キーワード | ||||||
| 主題言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | fascia | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_46ec | |||||
| 資源タイプ | thesis | |||||
| アクセス権 | ||||||
| アクセス権 | open access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
| 要約 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Background/Aim: Transanal total mesorectal excision (TaTME) remains a challenging technique for rectal dissection. This study aimed to evaluate the clinical and oncological outcomes of TaTME, compared to those of the laparoscopic TME (LaTME) in rectal cancer. Patients and Methods: Using propensity score-matched analyses, we analyzed retrospective data from 134 consecutive patients with rectal cancer who underwent TaTME or LaTME from January 2011 to June 2020 in our hospital. Clinical and oncological outcomes were evaluated. The primary endpoint was the 2-year local recurrence rate. Results: Before data analysis, significant group-dependent differences were observed only in the tumor height (p<0.01). After analysis, preoperative patient demographics were similar between the TaTME and LaTME groups. The operative time was significantly shorter in the TaTME group (p=0.02), and the rates of hand-sewn anastomosis and protective loop ileostomy were significantly higher (p<0.01). The TaTME group showed a null conversion to open surgery compared to the LaTME group (5.9%). The postoperative complications, including anastomotic leak, were comparable between the two groups. However, the rate of Clavien–Dindo grade III tended to be lower in the TaTME group (p=0.07). There were no statistically significant differences in terms of pathological findings, and the 2-year local recurrence rate was similar between the two groups (both 5.9%). Conclusion: TaTME based on embryology along the fascia is feasible and seems a safe alternative to LaTME in selected patients with rectal cancer when considering the conversion rate and the operative time. | |||||
| 内容記述言語 | en | |||||
| 要約 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | KOHEI YOSHIMITSU, SHINICHIRO MORI, KAN TANABE, MASUMI WADA, YUKI HAMADA, RYUTARO YASUDOME, HIROSHI KURAHARA, TAKAAKI ARIGAMI, KEN SASAKI, CHIHAYA KORIYAMA, MICHIYO HIGASHI, AKIHIRO NAKAJO and TAKAO OHTSUKA Transanal Total Mesorectal Excision Considering the Embryology Along the Fascia in Rectal Cancer Patients Anticancer Research August 2023, 43 (8) 3597-3605 https://doi.org/10.21873/anticanres.16539 |
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| 内容記述言語 | en | |||||
| 作成日 | ||||||
| 日付 | 2024-04-09 | |||||
| 日付タイプ | Collected | |||||
| ファイル（説明） | ||||||
| 内容記述 | 博士論文要約, 博士論文要旨, 最終試験結果の要旨, 論文審査の要旨 | |||||
| 公開者・出版者 | ||||||
| 出版者 | International Institute of Anticancer Research | |||||
| 出版者言語 | en | |||||
| 公開者・出版者 | ||||||
| 出版者 | 鹿児島大学 | |||||
| 出版者言語 | ja | |||||
| 備考 | ||||||
| 備考言語 | ja | |||||
| 備考 | 【指導教員:大塚隆生】要約公表の理由: 出版社版が公開不可のため | |||||
| date.appl | ||||||
| appl | 【学位申請日】2024-01-10 | |||||
| 学位名 | ||||||
| 学位名の言語 | ja | |||||
| 学位名 | 博士(医学) | |||||
| 学位名 | ||||||
| 学位名の言語 | en | |||||
| 学位名 | Doctor of Philosophy in Medical Science | |||||
| 学位授与機関名 | ||||||
| 学位授与機関識別子Scheme | kakenhi | |||||
| 学位授与機関識別子 | 17701 | |||||
| 学位授与機関名の言語 | ja | |||||
| 学位授与機関名 | 鹿児島大学 | |||||
| 学位授与年月日 | ||||||
| 学位授与年月日 | 2024-04-17 | |||||
| 学位授与番号 | ||||||
| 学位授与番号 | 甲総研第740号 | |||||
