{"_buckets": {"deposit": "2097fa75-d5f8-4feb-9b0d-63f6ce040cf5"}, "_deposit": {"created_by": 3, "id": "6006", "owners": [3], "pid": {"revision_id": 0, "type": "depid", "value": "6006"}, "status": "published"}, "_oai": {"id": "oai:ir.kagoshima-u.ac.jp:00006006", "sets": ["80"]}, "author_link": ["14880", "117942", "117941"], "item_8_alternative_title_18": {"attribute_name": "別言語のタイトル", "attribute_value_mlt": [{"subitem_alternative_title": "Development and treanment neurophysiological elucidation of the mechanism by bruxism-induced esophageal mucous membrane irritstion"}]}, "item_8_alternative_title_19": {"attribute_name": "タイトルよみ", "attribute_value_mlt": [{"subitem_alternative_title": "ショクドウ ネンマク シゲキ ニヨル ブラキシズム ユウハツ キコウ ノ シンケイ セイリガクテキ カイメイ ト チリョウホウ ノ カイハツ"}]}, "item_8_date_6": {"attribute_name": "作成日", "attribute_value_mlt": [{"subitem_date_issued_datetime": "2014-06-17"}]}, "item_8_description_4": {"attribute_name": "要約(Abstract)", "attribute_value_mlt": [{"subitem_description": "2011-2013年度科学研究費助成事業（基盤研究（C））研究成果報告書　課題番号：23593035　研究代表者：上村裕希（鹿児島大学・医歯（薬）学総合研究科・助教）", "subitem_description_type": "Other"}, {"subitem_description": "食道への酸逆流と咬筋筋活動及び侵害受容器との関連については不明な点が多く、本研究では侵害受容器に着目し、ラット食道粘膜へ酸・ペプシン刺激を負荷し、咬筋筋活動と侵害受容器の発現亢進について検討した。Wister系雄性ラットに生理食塩水、酸ペプシン溶液を注入し、咬筋活動と食道の侵害受容器について調べた。咬筋筋活動、侵害受容器の発現が酸ペプシン溶液群で有意に多かった。本結果から、容器の活性化によって酸・ペプシンの食道への刺激が中枢へと伝達され、咬筋筋活動に関与する可能性が考えられ、食道への酸・ペプシン暴露によって咬筋筋活動が誘発され、それは食道における侵害受容器との関連が示唆された。", "subitem_description_type": "Other"}, {"subitem_description": "Many questions about the context of the nociceptors and masseter muscle activity and acid  reflux into the esophagus, we focus on the nociceptors In this study, we loaded with acid—pepsin stimulation to rat esophageal mucosa, infringement and masseter muscle activity We investigated the enhanced expression of receptors. Was injected saline, the acid pepsin solution in Wister male rats, were examined for nociceptors esophagus and masseter muscle activity. Masseter muscle activity, expression of nociceptors was significantly in acid pepsin solution group. From this result, esophageal irritation of acid—pepsin is transmitted to the central by the activation of the vessel, likely to be involved in masseter muscle activity can be considered, masseter muscle activity is induced by acid—pepsin exposure to road , it was suggested to be associated with nociceptors in the esophagus.", "subitem_description_type": "Other"}]}, "item_8_full_name_2": {"attribute_name": "著者よみ", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "117941", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "カミムラ, ヒロキ"}]}]}, "item_8_full_name_3": {"attribute_name": "別言語の著者", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "117942", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "KAMIMURA, Hiroki"}]}]}, "item_8_publisher_23": {"attribute_name": "公開者・出版者", "attribute_value_mlt": [{"subitem_publisher": "鹿児島大学"}]}, "item_8_subject_15": {"attribute_name": "NDC", "attribute_value_mlt": [{"subitem_subject": "491", "subitem_subject_scheme": "NDC"}, {"subitem_subject": "493", "subitem_subject_scheme": "NDC"}]}, "item_8_text_24": {"attribute_name": "公開者よみ", "attribute_value_mlt": [{"subitem_text_value": "カゴシマ ダイガク"}]}, "item_8_text_25": {"attribute_name": "公開者別名", "attribute_value_mlt": [{"subitem_text_value": "Kagoshima University"}]}, "item_8_text_30": {"attribute_name": "NIIタイプ", "attribute_value_mlt": [{"subitem_text_value": "Research Paper"}]}, "item_8_text_41": {"attribute_name": "科研費番号 ", "attribute_value_mlt": [{"subitem_text_value": "23593035"}]}, "item_8_version_type_14": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "上村, 裕希"}], "nameIdentifiers": [{"nameIdentifier": "14880", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "1000050464467", "nameIdentifierScheme": "NRID", "nameIdentifierURI": " "}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2016-10-28"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "23593035_上村裕希.pdf", "filesize": [{"value": "640.1 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 640100.0, "url": {"label": "23593035_上村裕希.pdf", "url": "https://ir.kagoshima-u.ac.jp/record/6006/files/23593035_上村裕希.pdf"}, "version_id": "ff79a4c5-cdae-4b5f-ab1f-55e0350cb940"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "ブラキシズム", "subitem_subject_scheme": "Other"}, {"subitem_subject": "胃食道酸逆流", "subitem_subject_scheme": "Other"}, {"subitem_subject": "侵害受容器", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "research report", "resourceuri": "http://purl.org/coar/resource_type/c_18ws"}]}, "item_title": "食道粘膜刺激によるブラキシズム誘発機構の神経生理学的解明と治療法の開発", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "食道粘膜刺激によるブラキシズム誘発機構の神経生理学的解明と治療法の開発"}]}, "item_type_id": "8", "owner": "3", "path": ["80"], "permalink_uri": "http://hdl.handle.net/10232/24103", "pubdate": {"attribute_name": "公開日", "attribute_value": "2015-05-22"}, "publish_date": "2015-05-22", "publish_status": "0", "recid": "6006", "relation": {}, "relation_version_is_last": true, "title": ["食道粘膜刺激によるブラキシズム誘発機構の神経生理学的解明と治療法の開発"], "weko_shared_id": 3}