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NECROSIS AND REGENERATION OF THE SKELETAL MUSCLE WITHOUT A MARKED HEMORRHAGE INDUCED IN THE RAT BY ENVENOMATION OF TRIMERESURUS FLAVOVIRIDIS VENOM AND ITS COMPONENTS, PHOSPHOLIPASE A2 ISOZYMES
http://hdl.handle.net/10232/9810
http://hdl.handle.net/10232/9810b10cbeee-dfff-4e0f-a1c1-7ee641599bc4
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
AN1013531X_v38_p105-111.pdf (325.2 kB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2010-11-09 | |||||
| タイトル | ||||||
| タイトル | NECROSIS AND REGENERATION OF THE SKELETAL MUSCLE WITHOUT A MARKED HEMORRHAGE INDUCED IN THE RAT BY ENVENOMATION OF TRIMERESURUS FLAVOVIRIDIS VENOM AND ITS COMPONENTS, PHOSPHOLIPASE A2 ISOZYMES | |||||
| タイトル言語 | en | |||||
| 著者 |
KITANO, Motoo
× KITANO, Motoo× HIRANO, Masato× ISHIHARA, Takashi× HASHIMA, Taketomo× UMEMURA, Eri× YOSHIDA, Aichi× HATTORI, Shosaku× UEDA, Naoko× OHNO, Motonori |
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| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Trimeresurus flavoviridis (Tf) | |||||
| キーワード | ||||||
| 主題言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Envenomation | |||||
| キーワード | ||||||
| 主題言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Myotoxin | |||||
| キーワード | ||||||
| 主題言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Skeletal muscle | |||||
| キーワード | ||||||
| 主題言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Quadriceps femoris muscle (QFM) | |||||
| キーワード | ||||||
| 主題言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Myonecrosis | |||||
| キーワード | ||||||
| 主題言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Regeneration | |||||
| キーワード | ||||||
| 主題言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Myoblast | |||||
| キーワード | ||||||
| 主題言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | PhospholipasesA2 isozymes | |||||
| キーワード | ||||||
| 主題言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Hemorrhage | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| アクセス権 | ||||||
| アクセス権 | open access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
| 要約 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | A histopathological study of the lesions caused by sublethal doses of Trimeresurus flavoviridis (Tf) venom injected into the anterior thigh muscle (quadriceps femoris muscle; QFM) of rats was done. A dose of 50 μg of Tf venom (crude venom, and three kinds of the phospholipase A2 isozymes of Tf venom; [Asp49]PLA2, BPI and BPII) produced a large area of necrosis in QFM. Myonecrosis was evident 30 minutes after the injection, and over the following 72 hours the necrotic muscles remained acellular and devoid of inflammatory reaction except at the very edge where liquefaction necrosis associated with inflammatory infiltrate was marked from the beginning. Blood vessels in and around the necrotic foci were often involved in inflammatory changes and thrombosis, to some degree. However, marked hemorrhage was never noted. Phagocytosis of debris proceeded from the periphery, and after 24 hours the muscle was replaced by granulaion tissue containing many regenerating myoblastic cells. Interestingly, the myonecrogenic Tf venom itself may cause marked and extensive activation of muscle fiber regeneration, and the venom seems to be a great myotoxin but not a hemorrhagenic toxin for the rat. | |||||
| 内容記述言語 | en | |||||
| 要約 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | SECTION THREE: PEOPLE-NATURE INTERACTIONS: Report 5 | |||||
| 内容記述言語 | en | |||||
| 収録雑誌名 |
ja : 南太平洋海域調査研究報告 en : Occasional papers 巻 38, p. 105-111, 発行日 2003-02-28 |
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| 作成日 | ||||||
| 日付 | 2003-02-28 | |||||
| 日付タイプ | Issued | |||||
| ISSN | ||||||
| 収録物識別子タイプ | PISSN | |||||
| ISSN | 13450441 | |||||
| NII書誌ID（雑誌） | ||||||
| 収録物識別子タイプ | NCID | |||||
| NC ID | AN1013531X | |||||
| 出版タイプ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| NDC | ||||||
| 主題Scheme | NDC | |||||
| 主題 | 487 | |||||
| 公開者・出版者 | ||||||
| 出版者 | 鹿児島大学 | |||||
| 出版者言語 | ja | |||||
| 公開者・出版者 | ||||||
| 出版者 | Kagoshima University | |||||
| 出版者言語 | en | |||||
