{"_buckets": {"deposit": "9fec6fde-b186-4844-b0ac-007d572416c7"}, "_deposit": {"created_by": 3, "id": "13247", "owners": [3], "pid": {"revision_id": 0, "type": "depid", "value": "13247"}, "status": "published"}, "_oai": {"id": "oai:ir.kagoshima-u.ac.jp:00013247", "sets": ["80"]}, "author_link": ["118133", "118134", "118132"], "item_8_alternative_title_18": {"attribute_name": "別言語のタイトル", "attribute_value_mlt": [{"subitem_alternative_title": "Development of conditionally replicating adenovirus that treats human ES/iPS-derived tumor"}]}, "item_8_alternative_title_19": {"attribute_name": "タイトルよみ", "attribute_value_mlt": [{"subitem_alternative_title": "ヒト ES/iPS サイボウ ユライ ノ シュヨウ オ ヒョウテキ チリョウスル ゾウショクガタ アデノウイルス ノ カイハツ"}]}, "item_8_date_6": {"attribute_name": "作成日", "attribute_value_mlt": [{"subitem_date_issued_datetime": "2014-06-19"}]}, "item_8_description_4": {"attribute_name": "要約(Abstract)", "attribute_value_mlt": [{"subitem_description": "2011-2013年度科学研究費助成事業（挑戦的萌芽研究）研究成果報告書　課題番号：24659159　研究代表者：\n小戝健一郎（鹿児島大学・医歯（薬）学総合研究科・教授）", "subitem_description_type": "Other"}, {"subitem_description": "ヒトES細胞、iPS細胞を用いた再生医療技術の臨床応用において、混在した未分化細胞から生じる腫瘍の克服は、重要な課題である。研究者が癌治療用に独自開発したm-CRA（多因子で精密に癌特異化する増殖制御型アデノウイルスベクター）技術を用いて、この問題をある程度解決できることを示唆する科学的成果を得た。科学的にも独創的な研究であり、先端医療実現を進めるという点でも意義ある成果と思われる。", "subitem_description_type": "Other"}, {"subitem_description": "The tumor that is derived from the contaminated undifferentiated-cells is the major obstacle to the clinical application of human ES and/or iPS cell-based regenerative medicine. Here we developed a novel methodology that might conquer this obstacle to some degrees using m-CRA (conditionally replicating adenovirus with multiple tumor-specific factors), which we had initially developed for treating cancer. This methodology is not only a scientifically novel and original but also meaningful in terms of facilitating clinical development of these sorts of innovative therapy.", "subitem_description_type": "Other"}]}, "item_8_full_name_2": {"attribute_name": "著者よみ", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "118133", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "コサイ, ケンイチロウ"}]}]}, "item_8_full_name_3": {"attribute_name": "別言語の著者", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "118134", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "KOSAI, Kenichiro"}]}]}, "item_8_publisher_23": {"attribute_name": "公開者・出版者", "attribute_value_mlt": [{"subitem_publisher": "鹿児島大学"}]}, "item_8_subject_15": {"attribute_name": "NDC", "attribute_value_mlt": [{"subitem_subject": "491", "subitem_subject_scheme": "NDC"}]}, "item_8_text_24": {"attribute_name": "公開者よみ", "attribute_value_mlt": [{"subitem_text_value": "カゴシマ ダイガク"}]}, "item_8_text_25": {"attribute_name": "公開者別名", "attribute_value_mlt": [{"subitem_text_value": "Kagoshima University"}]}, "item_8_text_30": {"attribute_name": "NIIタイプ", "attribute_value_mlt": [{"subitem_text_value": "Research Paper"}]}, "item_8_text_41": {"attribute_name": "科研費番号 ", "attribute_value_mlt": [{"subitem_text_value": "24659159"}]}, "item_8_version_type_14": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "小戝, 健一郎"}], "nameIdentifiers": [{"nameIdentifier": "118132", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2016-10-31"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "23659159_小戝健一郎.pdf", "filesize": [{"value": "246.4 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 246400.0, "url": {"label": "23659159_小戝健一郎.pdf", "url": "https://ir.kagoshima-u.ac.jp/record/13247/files/23659159_小戝健一郎.pdf"}, "version_id": "190c81fa-34f5-4d3b-aa25-5382ec1c6e0b"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "再生医学", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "research report", "resourceuri": "http://purl.org/coar/resource_type/c_18ws"}]}, "item_title": "ヒトES/iPS細胞由来の腫瘍を標的治療する増殖型アデノウイルス技術の開発", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "ヒトES/iPS細胞由来の腫瘍を標的治療する増殖型アデノウイルス技術の開発"}]}, "item_type_id": "8", "owner": "3", "path": ["80"], "permalink_uri": "http://hdl.handle.net/10232/24083", "pubdate": {"attribute_name": "公開日", "attribute_value": "2015-05-21"}, "publish_date": "2015-05-21", "publish_status": "0", "recid": "13247", "relation": {}, "relation_version_is_last": true, "title": ["ヒトES/iPS細胞由来の腫瘍を標的治療する増殖型アデノウイルス技術の開発"], "weko_shared_id": 3}