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成人紫斑病性腎炎に対するステロイド療法の検討
http://hdl.handle.net/10232/00030361
http://hdl.handle.net/10232/00030361a24c6ca0-c31d-4d01-aed3-beb48d84a3c3
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
AN00040104_67_p27-32 (819.5 kB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2018-12-06 | |||||
| タイトル | ||||||
| タイトル | 成人紫斑病性腎炎に対するステロイド療法の検討 | |||||
| 言語 | ja | |||||
| タイトル | ||||||
| タイトル | Effectiveness of Steroid Therapy for Henoch-Schönlein Purpura Nephritis | |||||
| 言語 | en | |||||
| 著者 |
阿部, 正治
× 阿部, 正治× 猪俣, 美穂× 吉嶺, 陽仁× 古城, 卓真× 村岡, 良朗× 吉嶺, 陽造× 小山田, 美紀× 福元, まゆみ× 屋, 万栄× 徳永, 公紀× 野﨑, 剛× 井戸, 章雄 |
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| 言語 | ||||||
| 言語 | jpn | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Henoch-Schönlein purpura nephritis | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | tonsillectomy | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | steroid | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| 要約(Abstract) | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Purpose: Steroid therapy has been established for pediatric patients with Henoch-Schönlein purpura nephritis (HSPN). Therefore, adult patients with HSPN have been treated with steroid alone or combined with tonsillectomy. However the effect of steroid therapy with or without tonsillectomy in adult patients remains to be determined. This study aims to evaluate whether steroid therapy with or without tonsillectomy affects the clinical course of adult HSPN patients. Methods: We retrospectively investigated nine adult patients, including five men, with biopsy-proven HSPN from 2006 to 2012, followed by observation for more than 12 months (range: 19 to 97 months). Results: The median age of the patients was 36 years (range 20 to 72) at the time of renal biopsy. Three patients received steroid pulse therapy combined with tonsillectomy, and three received steroid therapy. In three additional patients, one was treated with an angiotensin II receptor blocker (ARB) and dilazep, one was treated with a Ca blocker, and the other did not receive any medication. Except for the patient receiving the Ca blocker, eight patients were in remission throughout the observation period. Notably, two of three patients treated with steroid pulse therapy and tonsillectomy and one of three with steroid exhibited a rapid decrease in urinary excretion of protein, resulting in remission within a year. Conclusions: All patients receiving steroid therapy with or without tonsillectomy were in remission. These results suggest that steroid therapy alone, regardless of tonsillectomy, is likely effective in adult patients with HSPN. |
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| 言語 | en | |||||
| 収録雑誌名 |
ja : 鹿児島大学医学雑誌 en : Medical journal of Kagoshima University 巻 67, 号 1-3, p. 27-32, 発行日 2015-12 |
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| 作成日 | ||||||
| 日付 | 2015-07 | |||||
| 日付タイプ | Issued | |||||
| ISSN | ||||||
| 収録物識別子タイプ | PISSN | |||||
| 収録物識別子 | 03685063 | |||||
| NII書誌ID（雑誌） | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AN00040104 | |||||
| 出版タイプ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| NDC | ||||||
| 主題Scheme | NDC | |||||
| 主題 | 493 | |||||
| 公開者・出版者 | ||||||
| 出版者 | 鹿児島大学 | |||||
| 言語 | ja | |||||
| 公開者・出版者 | ||||||
| 出版者 | Kagoshima University | |||||
| 言語 | en | |||||
