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Association of risk factors for atherosclerosis, including higb-sensitivity C-reactive protein, with carotid intima-media thickness, plaque score, and pulse wave velocity in a male population
http://hdl.handle.net/10232/00031072
http://hdl.handle.net/10232/00031072e281c192-15a5-415a-bfaa-f7343c8a7e9e
名前 / ファイル | ライセンス | アクション |
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Item type | 学位論文 / Thesis or Dissertation(1) | |||||
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公開日 | 2020-05-21 | |||||
タイトル | ||||||
タイトル | Association of risk factors for atherosclerosis, including higb-sensitivity C-reactive protein, with carotid intima-media thickness, plaque score, and pulse wave velocity in a male population | |||||
別言語のタイトル | ||||||
その他のタイトル | 男性における高感度CRPを含めた動脈硬化の危険因子と頸動脈内膜中膜複合体厚,頸動脈プラークスコア及び上腕足首脈波伝播速度との関連 | |||||
著者 |
小島, 聡子
× 小島, 聡子 |
|||||
著者よみ | ||||||
姓名 | オジマ, サトコ | |||||
別言語の著者 | ||||||
姓名 | Ojima, Satoko | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題言語 | en | |||||
主題Scheme | Other | |||||
主題 | intima-media thickness | |||||
キーワード | ||||||
主題言語 | en | |||||
主題Scheme | Other | |||||
主題 | plaque score | |||||
キーワード | ||||||
主題言語 | en | |||||
主題Scheme | Other | |||||
主題 | brachial-ankle pulse wave velocity | |||||
キーワード | ||||||
主題言語 | en | |||||
主題Scheme | Other | |||||
主題 | high blood pressure | |||||
キーワード | ||||||
主題言語 | en | |||||
主題Scheme | Other | |||||
主題 | high-sensitivity C-reactive protein | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_db06 | |||||
資源タイプ | doctoral thesis | |||||
アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
要約(Abstract) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Intima-media thickness (IMT), plaque score (PS) and brachial-ankle pulse wave velocity (baPWV) are non-invasive parameters for evaluation of atherosclerosis. There have been no reports investigating the associations between IMT, PS, or baPWV and known risk factors for atherosclerosis in the same participants. This study aimed to compare the contributed risk factors among IMT, PS, and baPWV.We enrolled 3,128 male participants who underwent health checkups. Carotid ultrasonography was used to measure IMT and PS, and baPWV was measured using an automatic device. We analyzed the association between these parameters and risk factors for atherosclerosis including obesity, smoking, alcohol, high blood pressure (BP), impaired fasting glucose (IFG), dyslipidemia (DL), and high-sensitivity C-reactive protein (hs-CRP).Multivariate logistic regression analysis revealed high IMT (>0.9 mm) to be independently associated with high BP. The presence of atherosclerosis (PS>1.1 mm) was independently associated with high BP, IFG, and DL. In addition, advanced atherosclerosis (PS>5.1 mm) showed a significant association with high BP, IFG, DL, log hs-CRP, and smoking. High baPWV (>1,600 cm/sec) was significantly correlated with high BP, IFG, and log hs-CRP. IMT, PS and baPWV are all associated with different risk factors among Japanese male participants. Only high BP was a common risk factor for all three parameters. Furthermore, hs-CRP was associated with advanced atherosclerosis, not but with the presence of atherosclerosis. | |||||
要約(Abstract) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Satoko Ojima, Takuro Kubozono, Shin Kawasoe, Takeko Kawabata, Masaaki Miyata, Hironori Miyahara, Shigeho Maenohara & Mitsuru Ohishi Association of risk factors for atherosclerosis, including high-sensitivity C-reactive protein, with carotid intima-media thickness, plaque score, and pulse wave velocity in a male population Hypertension Research volume 43, pages422–430 (2020) https://doi.org/10.1038/s41440-019-0388-2 |
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作成日 | ||||||
日付 | 2020-03-06 | |||||
出版タイプ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
NDC | ||||||
主題Scheme | NDC | |||||
主題 | 490 | |||||
ファイル(説明) | ||||||
内容記述タイプ | Other | |||||
内容記述 | 博士論文全文 | |||||
ファイル(説明) | ||||||
内容記述タイプ | Other | |||||
内容記述 | 博士論文要旨 | |||||
ファイル(説明) | ||||||
内容記述タイプ | Other | |||||
内容記述 | 最終試験結果の要旨 | |||||
ファイル(説明) | ||||||
内容記述タイプ | Other | |||||
内容記述 | 論文審査の要旨 | |||||
公開者・出版者 | ||||||
出版者 | Springer Nature | |||||
公開者・出版者 | ||||||
出版者 | 鹿児島大学 | |||||
公開者よみ | ||||||
公開者よみ | カゴシマ ダイガク | |||||
公開者別名 | ||||||
公開者別名 | Kagoshima University | |||||
備考 | ||||||
備考 | 【指導教員:大石充】 | |||||
date.appl | ||||||
【学位申請日】2020-01-08 | ||||||
学位名 | ||||||
学位名 | 博士(医学)Doctor of Philosophy in Medical Science | |||||
学位授与機関 | ||||||
学位授与機関識別子Scheme | kakenhi | |||||
学位授与機関識別子 | 17701 | |||||
学位授与機関名 | 鹿児島大学 | |||||
学位授与年月日 | ||||||
学位授与年月日 | 2020-03-25 | |||||
学位授与番号 | ||||||
学位授与番号 | 甲総研第548号 |