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  1. 医歯学総合研究科
  2. 医歯学総合研究科・博士論文

Association of risk factors for atherosclerosis, including higb-sensitivity C-reactive protein, with carotid intima-media thickness, plaque score, and pulse wave velocity in a male population

http://hdl.handle.net/10232/00031072
http://hdl.handle.net/10232/00031072
e281c192-15a5-415a-bfaa-f7343c8a7e9e
名前 / ファイル ライセンス アクション
Diss_小島_聡子_ISK548_2019.pdf Diss_小島_聡子_ISK548_2019 (584.5 kB)
Abstract_小島_聡子_4516810058_2019.pdf Abstract_小島_聡子_4516810058_2019 (82.8 kB)
Result_Ojima_Satoko_isk_548.pdf Result_Ojima_Satoko_isk_548 (245.3 kB)
Comments_Ojima_Satoko_isk_548.pdf Comments_Ojima_Satoko_isk_548 (94.4 kB)
Item type 学位論文 / Thesis or Dissertation(1)
公開日 2020-05-21
タイトル
タイトル Association of risk factors for atherosclerosis, including higb-sensitivity C-reactive protein, with carotid intima-media thickness, plaque score, and pulse wave velocity in a male population
別言語のタイトル
その他のタイトル 男性における高感度CRPを含めた動脈硬化の危険因子と頸動脈内膜中膜複合体厚,頸動脈プラークスコア及び上腕足首脈波伝播速度との関連
著者 小島, 聡子

× 小島, 聡子

WEKO 135828

小島, 聡子

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著者よみ
姓名 オジマ, サトコ
別言語の著者
姓名 Ojima, Satoko
言語
言語 eng
キーワード
主題言語 en
主題Scheme Other
主題 intima-media thickness
キーワード
主題言語 en
主題Scheme Other
主題 plaque score
キーワード
主題言語 en
主題Scheme Other
主題 brachial-ankle pulse wave velocity
キーワード
主題言語 en
主題Scheme Other
主題 high blood pressure
キーワード
主題言語 en
主題Scheme Other
主題 high-sensitivity C-reactive protein
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_db06
資源タイプ doctoral thesis
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
要約(Abstract)
内容記述タイプ Other
内容記述 Intima-media thickness (IMT), plaque score (PS) and brachial-ankle pulse wave velocity (baPWV) are non-invasive parameters for evaluation of atherosclerosis. There have been no reports investigating the associations between IMT, PS, or baPWV and known risk factors for atherosclerosis in the same participants. This study aimed to compare the contributed risk factors among IMT, PS, and baPWV.We enrolled 3,128 male participants who underwent health checkups. Carotid ultrasonography was used to measure IMT and PS, and baPWV was measured using an automatic device. We analyzed the association between these parameters and risk factors for atherosclerosis including obesity, smoking, alcohol, high blood pressure (BP), impaired fasting glucose (IFG), dyslipidemia (DL), and high-sensitivity C-reactive protein (hs-CRP).Multivariate logistic regression analysis revealed high IMT (>0.9 mm) to be independently associated with high BP. The presence of atherosclerosis (PS>1.1 mm) was independently associated with high BP, IFG, and DL. In addition, advanced atherosclerosis (PS>5.1 mm) showed a significant association with high BP, IFG, DL, log hs-CRP, and smoking. High baPWV (>1,600 cm/sec) was significantly correlated with high BP, IFG, and log hs-CRP. IMT, PS and baPWV are all associated with different risk factors among Japanese male participants. Only high BP was a common risk factor for all three parameters. Furthermore, hs-CRP was associated with advanced atherosclerosis, not but with the presence of atherosclerosis.
要約(Abstract)
内容記述タイプ Other
内容記述 Satoko Ojima, Takuro Kubozono, Shin Kawasoe, Takeko Kawabata, Masaaki Miyata, Hironori Miyahara, Shigeho Maenohara & Mitsuru Ohishi
Association of risk factors for atherosclerosis, including high-sensitivity C-reactive protein, with carotid intima-media thickness, plaque score, and pulse wave velocity in a male population
Hypertension Research volume 43, pages422–430 (2020)
https://doi.org/10.1038/s41440-019-0388-2
作成日
日付 2020-03-06
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
NDC
主題Scheme NDC
主題 490
ファイル(説明)
内容記述タイプ Other
内容記述 博士論文全文
ファイル(説明)
内容記述タイプ Other
内容記述 博士論文要旨
ファイル(説明)
内容記述タイプ Other
内容記述 最終試験結果の要旨
ファイル(説明)
内容記述タイプ Other
内容記述 論文審査の要旨
公開者・出版者
出版者 Springer Nature
公開者・出版者
出版者 鹿児島大学
公開者よみ
公開者よみ カゴシマ ダイガク
公開者別名
公開者別名 Kagoshima University
備考
備考 【指導教員:大石充】
date.appl
【学位申請日】2020-01-08
学位名
学位名 博士(医学)Doctor of Philosophy in Medical Science
学位授与機関
学位授与機関識別子Scheme kakenhi
学位授与機関識別子 17701
学位授与機関名 鹿児島大学
学位授与年月日
学位授与年月日 2020-03-25
学位授与番号
学位授与番号 甲総研第548号
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