{"_buckets": {"deposit": "efad1931-0106-4115-8549-1b4e98a1b8b7"}, "_deposit": {"created_by": 3, "id": "5121", "owners": [3], "pid": {"revision_id": 0, "type": "depid", "value": "5121"}, "status": "published"}, "_oai": {"id": "oai:ir.kagoshima-u.ac.jp:00005121", "sets": ["80"]}, "author_link": ["2140", "117923", "117924"], "item_8_alternative_title_18": {"attribute_name": "別言語のタイトル", "attribute_value_mlt": [{"subitem_alternative_title": "Search of organ specific tumor markers by N-glycan expression"}]}, "item_8_alternative_title_19": {"attribute_name": "タイトルよみ", "attribute_value_mlt": [{"subitem_alternative_title": "Nガタ トウサ オ モチイタ ゾウキ トクイテキ ガン シュヨウ マーカー ノ カイハツ"}]}, "item_8_date_6": {"attribute_name": "作成日", "attribute_value_mlt": [{"subitem_date_issued_datetime": "2012-05-30"}]}, "item_8_description_4": {"attribute_name": "要約(Abstract)", "attribute_value_mlt": [{"subitem_description": "2011-2011年度科学研究費助成事業(学術研究助成基金助成金(挑戦的萌芽))研究成果報告書　課題番号：23659657　研究代表者：夏越祥次 (鹿児島大学大学院医歯学総合研究科教授)", "subitem_description_type": "Other"}, {"subitem_description": "食道癌患者37例と健常者11例対象とし、血清中の糖鎖の網羅的解析を行い、食道癌に特異的な糖鎖マーカーを検索した。得られた糖鎖の発現パターンをもとに、健常者群と食道癌患者群との間でOPLS法による層別化が可能であった。健常者群と食道癌患者群間で、両者の層別化が可能な発現糖鎖が6つ抽出可能であった。その6糖鎖から食道癌患者を69.7%の正診率で判別することが可能であった。これらの糖鎖は食道癌に特異的マーカーとして利用できると考えられた。", "subitem_description_type": "Other"}, {"subitem_description": "We analyzed the serum N-glycan in 37 esophageal cancer patients and 11 healthy volunteers. N-glycan expression by using OPLS method was stratified between esophageal cancer patients and healthy volunteers on the base of glycan expression pattern, We extracted six N-glycan with statistical significance between esophageal cancer patients and healthy volunteers. According to these six markers, the accuracy rate was 69.7% to detect the esophageal cancer. These results show that six N-glycan may be a useful markers in detection of esophageal cancer.", "subitem_description_type": "Other"}]}, "item_8_full_name_2": {"attribute_name": "著者よみ", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "117923", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "ナツゴエ, ショウジ"}]}]}, "item_8_full_name_3": {"attribute_name": "別言語の著者", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "117924", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "NATSUGOE, Shoji"}]}]}, "item_8_publisher_23": {"attribute_name": "公開者・出版者", "attribute_value_mlt": [{"subitem_publisher": "鹿児島大学"}]}, "item_8_subject_15": {"attribute_name": "NDC", "attribute_value_mlt": [{"subitem_subject": "494", "subitem_subject_scheme": "NDC"}]}, "item_8_text_24": {"attribute_name": "公開者よみ", "attribute_value_mlt": [{"subitem_text_value": "カゴシマ ダイガク"}]}, "item_8_text_25": {"attribute_name": "公開者別名", "attribute_value_mlt": [{"subitem_text_value": "Kagoshima University"}]}, "item_8_text_30": {"attribute_name": "NIIタイプ", "attribute_value_mlt": [{"subitem_text_value": "Research Paper"}]}, "item_8_text_41": {"attribute_name": "科研費番号 ", "attribute_value_mlt": [{"subitem_text_value": "23659657"}]}, "item_8_version_type_14": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "夏越, 祥次"}], "nameIdentifiers": [{"nameIdentifier": "2140", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "1000070237577", "nameIdentifierScheme": "NRID", "nameIdentifierURI": " "}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2016-10-28"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "23659657seika.pdf", "filesize": [{"value": "431.5 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 431500.0, "url": {"label": "23659657seika.pdf", "url": "https://ir.kagoshima-u.ac.jp/record/5121/files/23659657seika.pdf"}, "version_id": "cde46113-d597-430f-9696-0138fd59fa61"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "食道癌", "subitem_subject_scheme": "Other"}, {"subitem_subject": "胃癌", "subitem_subject_scheme": "Other"}, {"subitem_subject": "大腸癌", "subitem_subject_scheme": "Other"}, {"subitem_subject": "膵臓癌", "subitem_subject_scheme": "Other"}, {"subitem_subject": "N結合型糖鎖", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "research report", "resourceuri": "http://purl.org/coar/resource_type/c_18ws"}]}, "item_title": "N型糖鎖を用いた臓器特異的癌腫瘍マーカーの開発", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "N型糖鎖を用いた臓器特異的癌腫瘍マーカーの開発"}]}, "item_type_id": "8", "owner": "3", "path": ["80"], "permalink_uri": "http://hdl.handle.net/10232/14805", "pubdate": {"attribute_name": "公開日", "attribute_value": "2014-12-22"}, "publish_date": "2014-12-22", "publish_status": "0", "recid": "5121", "relation": {}, "relation_version_is_last": true, "title": ["N型糖鎖を用いた臓器特異的癌腫瘍マーカーの開発"], "weko_shared_id": 3}