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Keratinolytic Properties of PrPSc-degrading Enzyme E77
http://hdl.handle.net/10232/8197
http://hdl.handle.net/10232/8197b36a714c-d3cb-4c47-81c6-8fe64abc9fb9
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
article05.pdf (683.0 kB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2009-06-01 | |||||
| タイトル | ||||||
| タイトル | Keratinolytic Properties of PrPSc-degrading Enzyme E77 | |||||
| 著者 |
Mitsuiki, Shinji
× Mitsuiki, Shinji× Takasugi, Mikako× Goto, Masatoshi× Kanouchi, Hiroaki× Oka, Tatsuzo |
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| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | prion | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | keratinase | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | protease | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| 要約(Abstract) | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | It is suggested that the keratinolytic activity of proteases are associated with the degrading activity of the abnormal type prion protein (PrPSc). We tried to analyze the keratinolytic properties of the PrPSc- degrading enzyme E77. E77 showed a much greater keratinolytic activity than proteinase K and subtilisin. The maximum activity of keratin was observed at a pH value of 12.0 at 65°C. E77 also showed a pH-independent adsorbability for keratin. These profiles of E77 were the same as the PrPSc -degrading enzyme NAPase, except for high alkaline conditions. E77 and NAPase showed lower collagenolytic and elastinolytic specificities. |
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| 収録雑誌名 |
鹿兒島大學農學部學術報告=Bulletin of the Faculty of Agriculture, Kagoshima University 巻 59, p. 37-42 |
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| 作成日 | ||||||
| 日付 | 2009-03-01 | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 04530845 | |||||
| NII書誌ID（雑誌） | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AN00040603 | |||||
| 出版タイプ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| NDC | ||||||
| 主題Scheme | NDC | |||||
| 主題 | 649 | |||||
| 公開者・出版者 | ||||||
| 出版者 | 鹿児島大学 | |||||
| 公開者別名 | ||||||
| 値 | Kagoshima University | |||||
