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ウナギ肝浮遊細胞における糖新生に及ぼす酵素阻害剤の影響
http://hdl.handle.net/10232/13289
http://hdl.handle.net/10232/1328901146bb4-391e-4b62-8ea4-bb855643c67b
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
AN00040498_v32_p167-171.pdf (485.9 kB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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| 公開日 | 2012-05-07 | |||||
| タイトル | ||||||
| タイトル | Effects of Several Enzyme-Inhibitors on Gluconeogenesis in the Isolated Liver Cells of Eel, Anguilla japonica | |||||
| タイトル言語 | en | |||||
| タイトル | ||||||
| タイトル | ウナギ肝浮遊細胞における糖新生に及ぼす酵素阻害剤の影響 | |||||
| タイトル言語 | ja | |||||
| 著者 |
林, 征一
× 林, 征一× 大城, 善太郎 |
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| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| 要約 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Effects of several enzyme-inhibitors on gluconeogenesis in the eel liver were investigated. 3-Mercaptopicolinic acid, an inhibitor of cytosolic phosphoenolpyruvate carboxykinase, inhibited gluconeogenesis from lactate and pyruvate by 60 and 76%, respectively. These inhibitions by 3-mercaptopicolinic acid were consistent with the intracellular distribution of phosphoenolpyruvate carboxykinase, of wich distribution in the liver cells was about 60% in cytosole and about 40% in mitochondria. Although it is known that 3-aminopicolinic acid is an activator of phosphoenolpyruvate carboxykinase and increases gluconeogenesis in mammalian liver, 3-aminopicolinic acid inhibited phosphoenolpyruvate carboxykinase and gluconeogenesis in the eel liver. Cycloserine, an inhibitor of transaminases, inhibited gluconeogenesis from lactate and pyruvate by 40 and 60%, respectively. These results were coincident with those obtained by using amino-oxyacetate, which is an inhibitor of transaminases. Malonate, an inhibitor of succinate dehydrogenase, had no effect on gluconeogenesis. Fluoro acetate, an inhibitor of malate synthetase, and maleic acid, an inhibitor of transaminase, inhibited slightly gluconeogenesis, but not significantly. |
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| 内容記述言語 | en | |||||
| 収録雑誌名 |
ja : 鹿児島大学水産学部紀要 en : Memoirs of Faculty of Fisheries Kagoshima University 巻 32, p. 167-171, 発行日 1983-12-25 |
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| 作成日 | ||||||
| 日付 | 1983-12-25 | |||||
| 日付タイプ | Issued | |||||
| ISSN | ||||||
| 収録物識別子タイプ | PISSN | |||||
| ISSN | 0453087X | |||||
| NII書誌ID（雑誌） | ||||||
| 収録物識別子タイプ | NCID | |||||
| NC ID | AN00040498 | |||||
| 出版タイプ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| NDC | ||||||
| 主題Scheme | NDC | |||||
| 主題 | 660 | |||||
| 公開者・出版者 | ||||||
| 出版者 | 鹿児島大学 | |||||
| 出版者言語 | ja | |||||
| 公開者・出版者 | ||||||
| 出版者 | Kagoshima University | |||||
| 出版者言語 | en | |||||
