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Histopathological Study on Dysbaric Osteonecrosis (DON) in Tibiae of Sheep with a Hyperbaric Exposure
http://hdl.handle.net/10232/113
http://hdl.handle.net/10232/113d75ba21e-1df1-4c64-8d72-c022bcb8680a
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
P17-P31.pdf (246.4 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2008-07-07 | |||||
| タイトル | ||||||
| タイトル | Histopathological Study on Dysbaric Osteonecrosis (DON) in Tibiae of Sheep with a Hyperbaric Exposure | |||||
| タイトル言語 | en | |||||
| 著者 |
Kitano, Motoo
× Kitano, Motoo× Lehner, Charles E.× Taya, Yasushi× Ozaki, Hiroshi S.× Takenaka, Masami× Kawashima, Mahito |
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| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | sheep tibia | |||||
| キーワード | ||||||
| 主題言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | hyperbar ic exposure | |||||
| キーワード | ||||||
| 主題言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | decompression sickness (DCS) | |||||
| キーワード | ||||||
| 主題言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | dysbaric osteonecrosis (DON) | |||||
| キーワード | ||||||
| 主題言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | thrombosis | |||||
| キーワード | ||||||
| 主題言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | increased tissue pressure | |||||
| キーワード | ||||||
| 主題言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | intraosseous nutrient artery | |||||
| キーワード | ||||||
| 主題言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | cutting cone | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 要約 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Previously we proposed a hypothesis that activation of blood coagulability in the intraosseous blood vessels contr ibutes impor tantly to produce decompression sickness (DCS) including dysbaric osteonecrosis (DON) after a hyperbar ic exposure. This paper presents evidence suppor ting this hypothesis. Crossbred, adult, female sheep were exposed to a three-hour exposure at 2.8-3.2 atm abs, using an experimental hyperbar ic chamber . They showed signs of bends in various legs soon after the exposure. Eight weeks after decompression insult, more or less marked and extensive pathologic findings of the bone mar row tissue wer e noted at the time of autopsy in their tibiae. In three tibiae of seven exper imental ・・sheep, a wide spread necrosis was found in the bone mar row, particular ly in the upper half of the shaft. ・・ In one of them, the large branches including the main ascending branch of the intraosseous nutrient artery were obliterated by organized thrombi at a little above the middle portion of the shaft of the right tibia. This arterial lesion seemed closely related to a widespread necrosis of the bone mar row of upper half of the shaft. Another conspicuous finding was formation of cutting cones, a repair process, observed in the cortical compact bone. Through formation of cutting cones, blood supply of the cortical bone recovered from the periosteum resulting in an active organization of necrotic bone mar row, where active formation of woven bone was observed. These suggest that provocative hyperbaric exposure can cause arterial thrombosis to produce early stage of necrosis of the bone tissues, and the subsequent repair processes can exaggerate the features of DON. |
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| 内容記述言語 | en | |||||
| 収録雑誌名 |
ja : 南太平洋研究 en : South Pacific Study 巻 18, 号 1, p. 17-31, 発行日 1997 |
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| 作成日 | ||||||
| 日付 | 1997-01-01 | |||||
| 日付タイプ | Issued | |||||
| ISSN | ||||||
| 収録物識別子タイプ | PISSN | |||||
| ISSN | 09160752 | |||||
| NII書誌ID（雑誌） | ||||||
| 収録物識別子タイプ | NCID | |||||
| NC ID | AN10088628 | |||||
| 出版タイプ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| 公開者・出版者 | ||||||
| 出版者 | 鹿児島大学 | |||||
| 出版者言語 | ja | |||||
| 公開者・出版者 | ||||||
| 出版者 | Kagoshima University | |||||
| 出版者言語 | en | |||||
