{"_buckets": {"deposit": "3506c7ca-1a6f-4882-8799-fd8f62d26f9e"}, "_deposit": {"created_by": 3, "id": "6796", "owners": [3], "pid": {"revision_id": 0, "type": "depid", "value": "6796"}, "status": "published"}, "_oai": {"id": "oai:ir.kagoshima-u.ac.jp:00006796", "sets": ["78"]}, "author_link": ["117096", "117095", "117098", "117099", "117097"], "item_6_biblio_info_5": {"attribute_name": "収録雑誌名", "attribute_value_mlt": [{"bibliographicPageEnd": "21", "bibliographicPageStart": "14", "bibliographicVolumeNumber": "6", "bibliographic_titles": [{"bibliographic_title": "Dendritic cells"}]}]}, "item_6_date_6": {"attribute_name": "作成日", "attribute_value_mlt": [{"subitem_date_issued_datetime": "1996-01-01"}]}, "item_6_description_4": {"attribute_name": "要約(Abstract)", "attribute_value_mlt": [{"subitem_description": "ln a HTLV-1 carrier Japanese man gastric T cell-rich B cell lymphoma occurred at 67 years of age and nodal T cell malignant lymphoma appeared at 72 years of age. The gastric T-cell rich B-cell Iymphoma formed an ulcerated tumor in the posterior wall of the body, involving up to the serosa and regional lymph nodes. A few lymphoma cells had cytoplasmic monoclonal κ and λ type immunoglobulin. Signals of HTLV-l pX Tax DNA sequence and stains of three antibodies against HTLV-1-encoded proteins  (gp46env, p40tax and p19gag) in some lymphoma cells suggested that this gastric lymphoma was a HTLV-1-related case. Six years later, large cell type T-cell malignant \nlymphoma occurred in left inguinal lymph node. Many S100+ dendritic cells and ysozyme+ cells were intermingling among the lymphoma cells. Some epithelioid cells among the lymphoma cells showed weak stains of the three antibodies against HTLV-l-encoded proteins. The PCR analysis showed oligoclonal rearrangement bands of TCRβ gene in the agar-gel electrophoresis. After three months\u0027 follow-up without chemotherapy, recurrent swelling of left inguinal lymph node and splenomegaly appeared. After chemotherapy the biopsied left inguinal lymph node showed necrosis and residual T cell malignant lymphoma. The uncommon features such as many T cells in the gastric lymphoma and many S100+ cells, many lysozyme+ cells and oligoclonal rearrangement of TCRβ gene in the nodal T-cell lymphoma might be induced by HTLV-1 infection. The patient has survived without any complaints. The HTLV-l-related lymphoid malignancies other than adult T-cell leukemia/lymphoma would be not-aggressive and might be the diseases in the microenvironment under the immunocompromised state in HTLV-1 carrier.", "subitem_description_type": "Other"}]}, "item_6_publisher_23": {"attribute_name": "公開者・出版者", "attribute_value_mlt": [{"subitem_publisher": "日本樹状細胞研究会"}]}, "item_6_source_id_9": {"attribute_name": "NII書誌ID", "attribute_value_mlt": [{"subitem_source_identifier": "AA11039557", "subitem_source_identifier_type": "NCID"}]}, "item_6_subject_15": {"attribute_name": "NDC", "attribute_value_mlt": [{"subitem_subject": "490", "subitem_subject_scheme": "NDC"}]}, "item_6_subject_20": {"attribute_name": "NIIsubject", "attribute_value_mlt": [{"subitem_subject": "医学", "subitem_subject_scheme": "Other"}]}, "item_6_text_25": {"attribute_name": "公開者別名", "attribute_value_mlt": [{"subitem_text_value": "Japanese Dendritic Cells Society"}]}, "item_6_text_30": {"attribute_name": "NIIタイプ", "attribute_value_mlt": [{"subitem_text_value": "Journal Article"}]}, "item_6_version_type_14": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_ab4af688f83e57aa", "subitem_version_type": "AM"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Hasui, Kazuhisa"}], "nameIdentifiers": [{"nameIdentifier": "117095", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Shirahama, Hiroshi"}], "nameIdentifiers": [{"nameIdentifier": "117096", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sueyoshi, Kazunobu"}], "nameIdentifiers": [{"nameIdentifier": "117097", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sato, Eiichi"}], "nameIdentifiers": [{"nameIdentifier": "117098", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Imakuma, Mitsuru"}], "nameIdentifiers": [{"nameIdentifier": "117099", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2016-10-28"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "DC(Hasui)1996.pdf", "filesize": [{"value": "351.3 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 351300.0, "url": {"label": "DC(Hasui)1996.pdf", "url": "https://ir.kagoshima-u.ac.jp/record/6796/files/DC(Hasui)1996.pdf"}, "version_id": "4f9b8ed3-9f4a-4efa-9ac0-0fdf31cd3b57"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "HTLV-1", "subitem_subject_scheme": "Other"}, {"subitem_subject": "malignant lymphoma", "subitem_subject_scheme": "Other"}, {"subitem_subject": "pathology", "subitem_subject_scheme": "Other"}, {"subitem_subject": "histochemistry", "subitem_subject_scheme": "Other"}, {"subitem_subject": "polymerase chain reaction", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Metachronous occurrence of gastric T-cell rich B-cell lymphoma and nodal T-cell lymphoma in a HTLV-1 carrier", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Metachronous occurrence of gastric T-cell rich B-cell lymphoma and nodal T-cell lymphoma in a HTLV-1 carrier"}]}, "item_type_id": "6", "owner": "3", "path": ["78"], "permalink_uri": "http://hdl.handle.net/10232/3740", "pubdate": {"attribute_name": "公開日", "attribute_value": "2010-04-13"}, "publish_date": "2010-04-13", "publish_status": "0", "recid": "6796", "relation": {}, "relation_version_is_last": true, "title": ["Metachronous occurrence of gastric T-cell rich B-cell lymphoma and nodal T-cell lymphoma in a HTLV-1 carrier"], "weko_shared_id": 3}