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Metachronous occurrence of gastric T-cell rich B-cell lymphoma and nodal T-cell lymphoma in a HTLV-1 carrier
http://hdl.handle.net/10232/3740
http://hdl.handle.net/10232/3740d277d1ad-9c05-4080-bcb2-6b9793137080
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
DC(Hasui)1996.pdf (351.3 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2010-04-13 | |||||
| タイトル | ||||||
| タイトル | Metachronous occurrence of gastric T-cell rich B-cell lymphoma and nodal T-cell lymphoma in a HTLV-1 carrier | |||||
| タイトル言語 | en | |||||
| 著者 |
Hasui, Kazuhisa
× Hasui, Kazuhisa× Shirahama, Hiroshi× Sueyoshi, Kazunobu× Sato, Eiichi× Imakuma, Mitsuru |
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| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | HTLV-1 | |||||
| キーワード | ||||||
| 主題言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | malignant lymphoma | |||||
| キーワード | ||||||
| 主題言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | pathology | |||||
| キーワード | ||||||
| 主題言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | histochemistry | |||||
| キーワード | ||||||
| 主題言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | polymerase chain reaction | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 要約 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | ln a HTLV-1 carrier Japanese man gastric T cell-rich B cell lymphoma occurred at 67 years of age and nodal T cell malignant lymphoma appeared at 72 years of age. The gastric T-cell rich B-cell Iymphoma formed an ulcerated tumor in the posterior wall of the body, involving up to the serosa and regional lymph nodes. A few lymphoma cells had cytoplasmic monoclonal κ and λ type immunoglobulin. Signals of HTLV-l pX Tax DNA sequence and stains of three antibodies against HTLV-1-encoded proteins (gp46env, p40tax and p19gag) in some lymphoma cells suggested that this gastric lymphoma was a HTLV-1-related case. Six years later, large cell type T-cell malignant lymphoma occurred in left inguinal lymph node. Many S100+ dendritic cells and ysozyme+ cells were intermingling among the lymphoma cells. Some epithelioid cells among the lymphoma cells showed weak stains of the three antibodies against HTLV-l-encoded proteins. The PCR analysis showed oligoclonal rearrangement bands of TCRβ gene in the agar-gel electrophoresis. After three months' follow-up without chemotherapy, recurrent swelling of left inguinal lymph node and splenomegaly appeared. After chemotherapy the biopsied left inguinal lymph node showed necrosis and residual T cell malignant lymphoma. The uncommon features such as many T cells in the gastric lymphoma and many S100+ cells, many lysozyme+ cells and oligoclonal rearrangement of TCRβ gene in the nodal T-cell lymphoma might be induced by HTLV-1 infection. The patient has survived without any complaints. The HTLV-l-related lymphoid malignancies other than adult T-cell leukemia/lymphoma would be not-aggressive and might be the diseases in the microenvironment under the immunocompromised state in HTLV-1 carrier. |
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| 内容記述言語 | en | |||||
| 収録雑誌名 |
en : Dendritic cells 巻 6, p. 14-21, 発行日 1996-01-01 |
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| 作成日 | ||||||
| 日付 | 1996-01-01 | |||||
| 日付タイプ | Issued | |||||
| NII書誌ID（雑誌） | ||||||
| 収録物識別子タイプ | NCID | |||||
| NC ID | AA11039557 | |||||
| 出版タイプ | ||||||
| 出版タイプ | AM | |||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
| NDC | ||||||
| 主題Scheme | NDC | |||||
| 主題 | 490 | |||||
| NII subject | ||||||
| 主題言語 | ja | |||||
| 主題Scheme | Other | |||||
| 主題 | 医学 | |||||
| 公開者・出版者 | ||||||
| 出版者 | 日本樹状細胞研究会 | |||||
| 出版者言語 | ja | |||||
| 公開者・出版者 | ||||||
| 出版者 | Japanese Dendritic Cells Society | |||||
| 出版者言語 | en | |||||
